GPR161 Antibody (1B2): sc-293409
- GPR161 Antibody (1B2) is a mouse monoclonal IgG2a κ GPR161 antibody provided at 100 µg/ml
- raised against amino acids 362-460 of GPR161 of human origin
- recommended for detection of GPR161 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GPR161 Antibody (1B2). This work is in progress.
GPR161 Antibody (1B2) is a mouse monoclonal IgG2a kappa light chain antibody that detects GPR161 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-GPR161 antibody (1B2) is available as the non-conjugated format. GPR161, also known as G protein-coupled receptor 161 or RE2, is a 529 amino acid protein that plays a crucial role in cellular signaling pathways as a member of the G-protein coupled receptor family. GPR161 is primarily localized to the cell membrane, where GPR161 functions as a multi-pass membrane protein, acting as an orphan receptor that transmits extracellular signals into the intracellular environment. GPR161′s importance lies in relaying signals from various extracellular stimuli, including hormones and neurotransmitters, which are vital for maintaining cellular communication and homeostasis. GPR161 undergoes alternative splicing, resulting in two isoforms that may have distinct functional roles, further emphasizing the complexity and significance of this receptor in physiological processes.
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GPR161 Antibody (1B2) References:
- Structural basis of G protein-coupled receptor function. | Schöneberg, T., et al. 1999. Mol Cell Endocrinol. 151: 181-93. PMID: 10411333
- False positive non-synonymous polymorphisms of G-protein coupled receptor genes. | Small, KM., et al. 2002. FEBS Lett. 516: 253-6. PMID: 11959142
- The structural basis of G-protein-coupled receptor function and dysfunction in human diseases. | Schöneberg, T., et al. 2002. Rev Physiol Biochem Pharmacol. 144: 143-227. PMID: 11987825
- Dissecting G-protein-coupled receptors: structure, function, and ligand interaction. | Schwalbe, H. and Wess, G. 2002. Chembiochem. 3: 915-9. PMID: 12362356
- Characterization of Gpr101 expression and G-protein coupling selectivity. | Bates, B., et al. 2006. Brain Res. 1087: 1-14. PMID: 16647048
- The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development. | Matteson, PG., et al. 2008. Proc Natl Acad Sci U S A. 105: 2088-93. PMID: 18250320
- G protein-coupled receptors. I. Diversity of receptor-ligand interactions. | Ji, TH., et al. 1998. J Biol Chem. 273: 17299-302. PMID: 9651309
- Identification of a novel G-protein coupled receptor expressed in distinct brain regions and a defined olfactory zone. | Raming, K., et al. 1998. Recept Channels. 6: 141-51. PMID: 9932290
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GPR161 Antibody (1B2) | sc-293409 | 100 µg/ml | $322.00 |