Anti-girdin Antibody H-6 è un monoclonale di topo IgG1 κ girdin antibody, citato in 1 pubblicazioni, fornito in 200 µg/ml
generato contro gli amminoacidi 1168-1294 mappati nella regione interna di girdin di origine human
girdin Antibody (H-6) é raccomandato per il rilevamento di girdin isoforms 1 and 2 di origine mouse, rat e human in WB, IP, IF e ELISA
girdin Antibody (H-6) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di girdin (H-6): sc-393757.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) are the preferred secondary detection reagents for girdin Antibody (H-6) for WB applications. These reagents are now offered in bundles with girdin Antibody (H-6) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
girdin Antibody (H-6) is a high quality monoclonal girdin antibody (also designated CCDC88A antibody, GIV antibody, APE antibody or GRDN antibody) suitable for the detection of the girdin protein of mouse, rat and human origin. girdin Antibody (H-6) is available as both the non-conjugated anti-girdin antibody form, as well as multiple conjugated forms of anti-girdin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Girdin, also known as CCDC88A (coiled-coil domain-containing protein 88A), APE, GRDN, GIV or HkRP1, is a 1,871 amino acid protein that, via interactions with phosphoinositides, localizes to the cell membrane and to the cytosol. Expressed ubiquitously, girdin functions to enhance the activity of PI 3-kinase-dependent phosphorylation of proteins, such as Akt1, thereby inducing the phosphorylation of downstream protein targets and, ultimately, regulating DNA replication and cellular proliferation. Additionally, girdin is crucial for cell migration and is responsible for both maintaining the structural integrity of the Actin cytoskeleton and for regulating the formation of Actin stress fibers. Girdin exists as a homodimer that can itself be phosphorylated-an event that delocalizes girdin from the cell membrane, thus allowing it to participate in cell migration events. Two isoforms of girdin exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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