Anti-ErbB-4 Antibody C-7 è un monoclonale di topo IgG2a (kappa light chain) ErbB-4 antibody fornito in 200 µg/ml
specifico per un epitopo mappato tra gli amminoacidi 1291-1308 al C-terminus di ErbB-4 di origine human
ErbB-4 Antibody (C-7) é raccomandato per il rilevamento di ErbB-4 di origine mouse, rat, human e avian in WB, IP, IF, IHC(P), FCM and ELISA; anche reattivo con ulteriori specie, incluse e equine, canine, bovine, porcine and avian
ErbB-4 Antibody (C-7) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
peptide bloccante, sc-8050 P
Vedi m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), le nostre alternative ricombinanti ai reagenti secondari convenzionali anti-mouse IgG altamente raccomandate.
Contattaci per ricevere un FREE 10 µg sample di ErbB-4 (C-7): sc-8050.
ErbB Inibitori per le analisi funzionali delle risposte cellulari a ErbB
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
ErbB-4 Antibody (C-7) is a high quality monoclonal ErbB-4 antibody (also designated ERBB4 antibody, erb-b2 receptor tyrosine kinase 4 antibody, or HER4 antibody) suitable for the detection of the ErbB-4 protein of mouse, rat and human origin. ErbB-4 Antibody (C-7) is available as both the non-conjugated anti-ErbB-4 antibody form, as well as multiple conjugated forms of anti-ErbB-4 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. The gene encoding ErbB-4 is expressed as a full length protein, which produces a short membrane-anchored cytoplasmic domain fragment and a long ectodomain fragment. The short fragment is heavily tyrosine phosphorylated and possesses tyrosine kinase catalytic activity toward an exogenous substrate. Proteolytic cleavage of ErbB-4 is promoted by the binding of heregulin. ErbB-4 is involved in cell proliferation and differentiation and its expression is highest in breast carcinoma cell lines, normal skeletal muscle, heart, pituitary, brain and cerebellum.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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