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DGCR14 Antibody (F-8) is a mouse monoclonal IgG1 antibody that detects DGCR14 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DGCR14, also known as ES2 protein, is a 476 amino acid nuclear protein that belongs to the DGCR14 family and plays a significant role in the etiology of velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder associated with various structural and functional anomalies. Nuclear localization of DGCR14 is crucial for assembling and operating spliceosomal complexes, which process pre-mRNA into mature mRNA. This processing regulates gene expression, and disruptions can lead to developmental issues observed in VCFS/DGS. Anti-DGCR14 antibody (F-8) provides reliable detection and analysis of DGCR14, supporting research into its role in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DGCR14 Antibody (F-8) | sc-398528 | 200 µg/ml | $322.00 | |||
DGCR14 Antibody (F-8): m-IgG Fc BP-HRP Bundle | sc-540939 | 200 µg Ab; 10 µg BP | $361.00 | |||
DGCR14 Antibody (F-8): m-IgG1 BP-HRP Bundle | sc-542475 | 200 µg Ab; 20 µg BP | $361.00 |