CTGF Antibody (6B13): sc-101586

CTGF Antibody (6B13) is a mouse monoclonal IgG1 antibody specifically designed to recognize Connective Tissue Growth Factor (CTGF), also known as CCN2 or Hypertrophic Chondrocyte-Specific Gene Product 24 (Hcs24). Anti-CTGF antibody (6B13) targets recombinant human CTGF and reliably detects CTGF from mouse, rat, and human sources using western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry (with or without antigen retrieval), and enzyme-linked immunosorbent assay (ELISA). CTGF is a crucial member of the CCN family of immediate early proteins, playing a significant role in cell proliferation, migration, and extracellular matrix production, which are essential processes in tissue development, repair, and fibrosis. As a cysteine-rich secreted protein, CTGF is produced by endothelial cells, fibroblasts, smooth muscle cells, and myofibroblasts, and expression is notably increased in various fibrotic diseases, including proliferative and fibrogenic renal disorders. Additionally, CTGF functions as a growth factor for vascular smooth muscle cells, promoting growth and migration, which is important in the study of vascular diseases and atherosclerosis. The upregulation of CTGF in fibrotic conditions underscores importance in the pathogenesis of these diseases, making CTGF a valuable target for research and therapeutic intervention. Available in a non-conjugated form, CTGF (6B13) antibody offers versatility for diverse experimental applications, ensuring accurate and consistent detection of CTGF in studies focused on fibrosis, tissue remodeling, and vascular biology.

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Contains Mercury: All HRP conjugates (including bundle forms) contain thiomersal, a mercury compound. Do not dispose in trash. Dispose as hazardous chemical waste according to local, state and federal regulations.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CTGF Antibody (6B13) has 48 citations in a variety of scientific publications.

Primary antibodies like Anti-CTGF Antibody (6B13) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CTGF Antibody (6B13) Specifications

Alternate Product Name: CTGF

Product Clone Name: 6B13

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: CTGF

Epitope Species: human

Product Reactivity/Detection: CTGF

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 50 µg IgG₁ in 0.5 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 48 citations in various scientific publications

Available Conjugates/Forms for CTGF Antibody (6B13): N/A

The preferred CTGF antibody is CTGF Antibody (E-5): sc-365970.