CD24 Antibody (2Q1282): sc-70598
- CD24 Antibody (2Q1282) is a mouse monoclonal IgG1 κ, cited in 4 publications, provided at 200 µg/ml
- raised against NALM-1 human pre-B leukemia cell line
- recommended for detection of CD24 of mouse, rat and human origin by WB, IP, IF and FCM
- See CD24 (SN3): sc-19585 for CD24 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CD24 Antibody (2Q1282) for WB applications. These reagents are now offered in bundles with CD24 Antibody (2Q1282) (see ordering information below).
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CD24 Antibody (2Q1282) is a mouse monoclonal IgG1 antibody that detects CD24 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CD24 is a glycosylphosphatidylinositol (GPI)-anchored membrane sialoglycoprotein predominantly expressed on pro-B, pre-B, and mature B cells, with expression diminishing following B cell activation. CD24 is also present on granulocytes and a small subset of thymocytes and neuroblastomas, but absent in plasma cells. CD24 plays a crucial role in regulating B cell proliferation and differentiation, serving as an important marker in hematological malignancies and various solid tumors. CD24 localization can shift from an apical position to a cytoplasmic distribution, serving as a surrogate marker for stromal invasion in ovarian serous tumors of borderline malignancy. As a differentiation marker for B cells, CD24 is expressed on mature resting B cells and disappears upon stimulation, highlighting CD24′s importance in understanding B cell biology and cancer research. Anti-CD24 antibody (2Q1282) serves as an essential tool for researchers investigating B cell development and tumor biology.
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CD24 Antibody (2Q1282) References:
- Associations between CD24 gene polymorphisms and inflammatory bowel disease: A meta-analysis. | Huang, XL., et al. 2015. World J Gastroenterol. 21: 6052-9. PMID: 26019472
- Identification of CD24 as a marker for tumorigenesis of melanoma. | Tang, MR., et al. 2018. Onco Targets Ther. 11: 3401-3406. PMID: 29928131
- Role of STAT3 dependent SOX2 and CD24 expression in melanoma cell adaptive resistance towards targeted therapies. | Hüser, L., et al. 2019. Oncotarget. 10: 1662-1663. PMID: 30899437
- Behavioral Characterizing of CD24 Knockout Mouse-Cognitive and Emotional Alternations. | Nitzan, K., et al. 2021. J Pers Med. 11: PMID: 33562144
- CD24 Contributes to Treatment Effect in ABC-DLBCL Patients with R-CHOP Resistance. | Qiao, LY., et al. 2021. Pharmgenomics Pers Med. 14: 591-599. PMID: 34079334
- Predictors of the CD24/CD11b Biomarker among Healthy Subjects. | Shapira, S., et al. 2021. J Pers Med. 11: PMID: 34575716
- CD24 Is a Prognostic Marker for Multiple Myeloma Progression and Survival. | Gross Even-Zohar, N., et al. 2022. J Clin Med. 11: PMID: 35629039
- PARP1 controls the transcription of CD24 by ADP-ribosylating the RNA helicase DDX5 in pancreatic cancer. | Chen, K., et al. 2023. Int J Biochem Cell Biol. 155: 106358. PMID: 36584909
- Engineering nanoparticles boost TNBC therapy by CD24 blockade and mitochondrial dynamics regulation. | Zhao, M., et al. 2023. J Control Release. 355: 211-227. PMID: 36736908
- Attenuated Salmonella carrying siRNA-CD24 improved the effect of oxaliplatin on HCC. | Li, B., et al. 2023. Int Immunopharmacol. 124: 111025. PMID: 37827056
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD24 Antibody (2Q1282) | sc-70598 | 200 µg/ml | $322.00 | |||
CD24 Antibody (2Q1282): m-IgG Fc BP-HRP Bundle | sc-539299 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD24 Antibody (2Q1282): m-IgG1 BP-HRP Bundle | sc-541390 | 200 µg Ab; 20 µg BP | $361.00 |