Anti-CASKIN2 Antibody D-9 è un monoclonale di topo IgG2b (kappa light chain) CASKIN2 antibody fornito in 200 µg/ml
generato contro gli amminoacidi 338-515 mappati nella regione interna di CASKIN2 di origine human
CASKIN2 Antibody (D-9) é raccomandato per il rilevamento di CASKIN2 di origine mouse, rat e human in WB, IP, IF e ELISA
CASKIN2 Antibody (D-9) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
Contattaci per ricevere un FREE 10 µg sample di CASKIN2 (D-9): sc-377512.
m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CASKIN2 Antibody (D-9) for WB applications. These reagents are now offered in bundles with CASKIN2 Antibody (D-9) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CASKIN2 Antibody (D-9) is a high quality monoclonal CASKIN2 antibody (also designated CASKIN2 antibody) suitable for the detection of the CASKIN2 protein of mouse, rat and human origin. CASKIN2 Antibody (D-9) is available as both the non-conjugated anti-CASKIN2 antibody form, as well as multiple conjugated forms of anti-CASKIN2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. CASKIN2 (CASK interacting protein 2), also known as ANKS5B, is a 1,202 amino acid protein that localizes to the cytoplasm and contains one SH3 domain, two SAM domains and six ANK repeats. Expressed ubiquitously with highest levels present in fetal and adult liver tissue, CASKIN2 interacts with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. The gene encoding CASKIN2 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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