Gβ 2 Activators
G protein subunit beta 1 (Gβ1) activators are a class of molecules that specifically enhance the function or action of the Gβ1 subunit of heterotrimeric G proteins. G proteins are a family of proteins involved in intracellular signal transduction, acting as molecular switches inside cells. The heterotrimeric G proteins consist of three different subunits: α, β, and γ, with the Gβ1 subunit being one of the variants of the β subunit. These proteins play a critical role in cellular communication and the regulation of various cellular processes, relaying signals from cell surface receptors to their respective intracellular targets. Activators of the Gβ1 subunit amplify the signaling capacity of this protein, either by promoting its association with other subunits or by modulating its interactions with downstream effectors.
The exact mechanism by which Gβ1 activators exert their effects can vary depending on the specific molecule in question. Some activators may bind directly to the Gβ1 subunit, causing conformational changes that favor its activity. Others might function indirectly, by stabilizing the Gβ1 subunit in its active state or by inhibiting its negative regulators. These activators have been studied in various biological contexts, revealing the intricate roles of Gβ1 in cellular physiology. Furthermore, a deeper understanding of these activators can offer insights into the fundamental principles of G protein signaling and its intricate regulatory mechanisms. Through continued research, scientists aim to elucidate the precise molecular details by which Gβ1 activators function and their broader implications in cellular signaling pathways.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, a metabolite of vitamin A, modulates gene expression. Its potential role in affecting GNB1 expression may stem from its broad regulatory effects on cell differentiation and development. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin stimulates adenylate cyclase, leading to increased cAMP levels. Elevated cAMP levels might induce changes in GNB1 expression as part of a broader cellular response. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a synthetic glucocorticoid, affects gene transcription and protein synthesis. The modulation of GNB1 expression might result from its extensive gene regulatory activities. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has diverse cellular effects, including signaling pathway modulation. Its impact on cell signaling and transcription factors could indirectly influence GNB1 expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride inhibits GSK3β and affects the Wnt signaling pathway. Its potential influence on GNB1 expression might be indirect through changes in this pathway. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC). This activation can potentially affect GNB1 expression among other cellular responses. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, a key regulator of cell growth and metabolism. Its potential effect on GNB1 expression may arise from broader changes in cellular processes stemming from mTOR inhibition. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate, an HDAC inhibitor, alters histone acetylation. This change in epigenetic regulation might influence GNB1 expression among other genes. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane activates the Nrf2 signaling pathway, influencing the expression of multiple genes. This activation might indirectly lead to changes in GNB1 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
TSA, another HDAC inhibitor, affects gene expression by modulating histone acetylation. Its potential impact on GNB1 expression may arise from this epigenetic regulation. | ||||||