


WSTF Antibody (BAZ1H4H9) is a mouse monoclonal IgG1 antibody that detects WSTF in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). WSTF, or Williams Syndrome transcription factor, is encoded by the BAZ1B gene and plays a crucial role in chromatin remodeling and transcriptional modulation, which are essential processes for proper gene expression and cellular function. WSTF is ubiquitously expressed in both adult and fetal tissues, highlighting its importance during development. WSTF features several structural elements that facilitate its function, including a PHD finger, which is a zinc-finger-like motif rich in cysteine that recognizes specific histone modifications, and a bromodomain that mediates interactions with acetylated histones, thereby influencing chromatin structure and accessibility. Additionally, WSTF interacts with various nuclear proteins, further underscoring its role in regulating transcriptional networks. The significance of WSTF is particularly evident in the context of Williams Syndrome, where its deletion contributes to the developmental disorder, making anti-WSTF antibody (BAZ1H4H9) a valuable tool for researchers studying chromatin dynamics and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WSTF Antibody (BAZ1H4H9) | sc-81426 | 100 µg/ml | $339.00 |