Anticorps WDR77 (A-4): sc-376556
- L'Anticorps WDR77 (A-4) est un monoclonal de souris IgG2a κ, cité dans 1 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 43-342 situés au niveau C-terminus de WDR77 d'origine human
- recommandé pour la détection de WDR77 d'origine human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps WDR77 (A-4) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps WDR77 (A-4)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. Proteins that contain WD-repeats participate in a wide range of cellular functions, however they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR77 (WD-repeat domain 77), also known as MEP50, is a 342 amino acid protein that contains five WD-repeats and is thought to regulate the early assembly of U snRNPs. Additionally, WDR77 functions as a component of a PRMT5-containing methyltransferase complex that converts arginines to dimethylarginines in a variety of spliceosomal Sm proteins. This conversion subsequently targets Sm proteins to the survival of motor neurons (SMN) complex where they are assembled into ribonucleoprotein core particles. Based on its involvement with the methyltransferase complex, WDR77 is thought to be involved in the development of testicular tumors, suggesting a role in carcinogenesis.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps WDR77 (A-4) | sc-376556 | 200 µg/ml | $316.00 | |||
WDR77 (A-4): m-IgG Fc BP-HRP Kit | sc-537989 | 200 µg Ab; 10 µg BP | $354.00 | |||
WDR77 (A-4): m-IgGκ BP-HRP Kit | sc-535492 | 200 µg Ab; 40 µg BP | $354.00 | |||
WDR77 (A-4): m-IgG2a BP-HRP Kit | sc-548173 | 200 µg Ab; 10 µg BP | $354.00 |