WDR77 Inhibitors
Regarding the chemical class WDR77 Inhibitors, these compounds represent a diverse group that can interact with cellular signaling pathways potentially linked to WDR77. Their mechanisms of action include antagonizing the androgen receptor, inhibiting bromodomains and histone deacetylases, and targeting key signaling pathways such as PI3K and mTOR. These inhibitors range from synthetic molecules specifically designed to target receptor interactions, like Enzalutamide and Bicalutamide, to broader-acting agents like LY294002 and Rapamycin.
Their action is centered around modulating cellular processes where WDR77 plays a role, particularly in cancer development and progression. By targeting these pathways, these inhibitors aim to indirectly influence the activity of WDR77, especially in contexts like prostate cancer where it is implicated in androgen receptor signaling.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MDV3100 | 915087-33-1 | sc-364354 sc-364354A | 5 mg 50 mg | $245.00 $1051.00 | 7 | |
Androgen receptor antagonist, can interfere with pathways involving WDR77 in prostate cancer. | ||||||
Bicalutamide | 90357-06-5 | sc-202976 sc-202976A | 100 mg 500 mg | $42.00 $146.00 | 27 | |
Another androgen receptor antagonist, potentially disrupting WDR77-associated signaling in cancer cells. | ||||||
Flutamide | 13311-84-7 | sc-204757 sc-204757A sc-204757D sc-204757B sc-204757C | 1 g 5 g 25 g 500 g 1 kg | $47.00 $156.00 $171.00 $525.00 $941.00 | 4 | |
Androgen receptor blocker, may influence WDR77-mediated pathways in prostate cancer. | ||||||
Apalutamide | 956104-40-8 | sc-507442 | 5 mg | $290.00 | ||
Inhibits androgen receptor, could disrupt WDR77's interaction with this receptor in cancer cells. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
Bromodomain inhibitor, can affect transcription factors associated with WDR77. | ||||||
GSK 525762A | 1260907-17-2 | sc-490339 sc-490339A sc-490339B sc-490339C sc-490339D | 5 mg 10 mg 50 mg 100 mg 1 g | $300.00 $540.00 $940.00 $1680.00 $5900.00 | ||
Bromodomain inhibitor, might impact WDR77-related gene expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor, could influence pathways associated with WDR77 in cell proliferation and survival. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor, may impact pathways related to cell growth where WDR77 is involved. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another histone deacetylase inhibitor, could influence WDR77-related gene expression. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Disrupts microtubule function, might indirectly affect WDR77's role in cell division and proliferation. | ||||||