Vacuolar sorting proteins (VPSs) are required for proper trafficking of endocytic and biosynthetic proteins to the vacuole and play an important role in the budding process of cells. VPS41 (vacuolar protein sorting 41), also known as HVPS41, is an 854 amino acid protein that contains one clathrin repeat and one RING-type zinc finger. Existing as two alternatively spliced isoforms, designated short and long, VPS41 is required for proper vacuolar assembly and vacuolar traffic, playing a role in the formation and fusion of transport vesicles from the Golgi. The gene encoding VPS41 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps VPS41 (E-10) | sc-377271 | 200 µg/ml | $316.00 |