Vacuolar sorting proteins (VPSs) are required for proper trafficking of endocytic and biosynthetic proteins to the vacuole and play an important role in the budding process of cells. VPS26 (vacuolar protein sorting 26), also known as VPS26A, HB58 or PEP8A, is a 327 amino acid protein that localizes to both the cytoplasm and to the endosomal membrane and exists as a component of the multi-subunit retromer complex. Specifically, the retromer complex relies on a variety of proteins, including VPS26, VPS26B and VPS35, all of which are responsible for the retrograde transport of proteins from endosomes to the trans-golgi network. VPS26 is expressed at high levels in heart, liver, kidney, placenta and skeletal muscle, where it plays an important role in protein trafficking. Multiple isoforms of VPS26 exist due to alternative splicing events.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps VPS26 (10L3) | sc-135606 | 100 µg/ml | $333.00 |