

VPS26 Antibody (10L3) is a mouse monoclonal IgG2a antibody that detects VPS26 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). VPS26, also known as vacuolar protein sorting 26 or VPS26A, is a crucial 327 amino acid protein that plays a significant role in the retrograde transport of proteins from endosomes to the trans-Golgi network, functioning as a key component of the multi-subunit retromer complex. This complex is essential for the proper trafficking of endocytic and biosynthetic proteins to the vacuole, which is vital for maintaining cellular homeostasis and facilitating various cellular processes. VPS26 is predominantly expressed in tissues such as the heart, liver, kidney, placenta, and skeletal muscle, highlighting VPS26′s importance in protein sorting and trafficking in these organs. Notably, VPS26 undergoes alternative splicing, resulting in multiple isoforms that may have distinct functions or regulatory mechanisms, further emphasizing the complexity and significance of VPS26 in cellular dynamics. Anti-VPS26 antibody (10L3) is an invaluable tool for researchers studying the mechanisms of protein transport and the role of the retromer complex in various physiological and pathological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VPS26 Antibody (10L3) | sc-135606 | 100 µg/ml | $339.00 |