Anticorps Ubr1 (24-Z): sc-100626
- L'Anticorps Ubr1 (24-Z) est un monoclonal de souris IgG1 κ, cité dans 4 publications, fourni en 100 µg/ml
- dirigé contre la Ubr1 recombinante d'origine human
- recommandé pour la détection de Ubr1 d'origine human par WB, IP et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire Ubr1 (24-Z). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The N-end rule relates the in vivo half-life of a protein to the composition of its N-terminal residues. The N-end rule pathway is part of the ubiquitin system, which involves a three-step mechanism. Proteins targeted for degradation are bound on their N-terminal residue by Ubr1 (also designated E3 alpha and N-recognin), which catalyzes the covalent attachment of ubiquitin to the protein substrate. Two zinc finger domains and the RING-H2 finger domain of Ubr1 are essential for substrate recognition. Ubr1 is located on mouse chromosome 2 and on human chromosome 15 in the syntenic region. Ubr1 is ubiquitously expressed in adult mouse, with the highest expression detected in skeletal muscle and heart. In mouse embryo, Ubr1 is primarily expressed in the branchial arches and in the tail and limb buds.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Ubr1 (24-Z) | sc-100626 | 100 µg/ml | $333.00 |