The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM23 (Tripartite motif-containing protein 23), also known as ARD1, ARFD1 or RNF46, is a 574 amino acid intracytoplasmic membrane protein that associates with the Golgi apparatus and with lysosomal structures. Belonging to both the TRIM protein family and the ADP ribosylation factor family of guanine nucleotide-binding proteins, TRIM23 plays a role in the formation of intracellular transport vesicles and aids in the movement of vesicles from one compartment to another. Additionally, TRIM23 interacts with cytohesin-1, an association that is thought to activate TRIM23 function. Three isoforms of TRIM23, designated alpha, beta and gamma, are expressed due to alternative splicing events.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TRIM23 (8H9) | sc-135587 | 100 µg/ml | $333.00 |