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Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor V (Factor V, FV, proaccelerin, labile factor) is a 2196 amino acid, single chain glycoprotein that is cleaved by Thrombin to yield an active, Ca2+-dependent dimer that is essential to the blood coagulation cascade. Together with catalytic Factor Xa and Ca2+ on the surface of platelets or endothelial cells, Factor Va coordinates into a Prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Tissue factor (TF), also designated coagulation Factor III) is a cell surface glycoprotein that enables cells to initiate blood coagulation cascades. It functions as a high-affinity receptor for coagulation Factor VII.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TF (C-7) | sc-393657 | 200 µg/ml | $316.00 | |||
TF (C-7): m-IgG Fc BP-HRP Kit | sc-538272 | 200 µg Ab; 10 µg BP | $354.00 | |||
TF (C-7): m-IgGκ BP-HRP Kit | sc-535850 | 200 µg Ab; 40 µg BP | $354.00 | |||
TF (C-7): m-IgG1 BP-HRP Kit | sc-545615 | 200 µg Ab; 20 µg BP | $354.00 |