Anticorps SULT2A1 (C-5): sc-166109
- L'Anticorps SULT2A1 (C-5) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 1-285 correspondant à la séquence totale de SULT2A1 d'origine human
- recommandé pour la détection de SULT2A1 d'origine human par WB, IP, IF, IHC(P) et ELISA
- m-IgG Fc BP-HRP et m-IgG1 BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps SULT2A1 (C-5) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps SULT2A1 (C-5) (voir Informations pour la commande ci-dessous).
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones. Members of the three groups comprising this superfamily show selectivity to certain substrate compounds. SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines, and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds. SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids and bile acids, and is highly expressed in adrenal and liver tissues. SULT2A1 plays a role in hepatic cholesterol homeostasis. SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, which are transcribed from the same gene by alternative splicing of their first exons. Both isoforms are highly selective for the sulphation of 3β-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA and androstenediol. SULT2B1b is expressed in prostate, skin, placenta and lung.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SULT2A1 (C-5) | sc-166109 | 200 µg/ml | $316.00 | |||
SULT2A1 (C-5): m-IgG Fc BP-HRP Kit | sc-540016 | 200 µg Ab; 10 µg BP | $354.00 | |||
SULT2A1 (C-5): m-IgG1 BP-HRP Kit | sc-541845 | 200 µg Ab; 20 µg BP | $354.00 |