The StARD (steroidogenic acute regulatory protein-related lipid transfer (START) domain containing) family of proteins is comprised of fifteen different members. All members contain the characteristic START domain and are believed to play key roles in the metabolism and transport of lipids. The StARD proteins are grouped into six subfamilies based on their START domain sequences. StARD8, StARD12 and StARD13 constitute one subfamily, namely the RhoGAP START group. StARD8, also known as DLC3 (deleted in liver cancer protein 3) or STARTGAP3, is a RhoGAP protein specific for Rho A and Cdc42. Localizing to focal adhesions, StARD8 contains one RhoGAP domain, one SAM (sterile alpha motif) domain and one START domain. Overexpression of StARD8 in various cancer cell lines represses cell proliferation and colony formation, implying that StARD8 acts as a tumor suppressor and plays a role in the regulation of cell growth.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps StARD8 (A-8) | sc-166444 | 200 µg/ml | $316.00 | |||
StARD8 (A-8): m-IgG Fc BP-HRP Kit | sc-537490 | 200 µg Ab; 10 µg BP | $354.00 | |||
StARD8 (A-8): m-IgGκ BP-HRP Kit | sc-534769 | 200 µg Ab; 40 µg BP | $354.00 | |||
StARD8 (A-8): m-IgG1 BP-HRP Kit | sc-545202 | 200 µg Ab; 20 µg BP | $354.00 |