SNX29 (sorting nexin-29), also known as RUNDC2A, is an 813 amino acid protein that contains one PX (phox homology) domain and one RUN domain. SNX29 exists as two alternatively spliced isoforms and belongs to the sorting nexin family. The gene that encodes SNX29 consists of more than 522,000 bases and maps to human chromosome 16p.13.13. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders, such as giant axonal neuropathy, Rubinstein-Taybi syndrome and Crohn's disease. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SNX29 (4B12) | sc-134432 | 100 µg/ml | $333.00 |