ACCÈS RAPIDE AUX LIENS
SNRPA (small nuclear ribonucleoprotein polypeptide A), also known as U1A (U1 snRNP protein A), is a component of the RNA spliceosome, a complex of proteins that are required for the precise excision of introns from pre-messenger RNA (pre-mRNA). Localizing to the nucleus, SNRPA contains two RRM (RNA recognition motif) domains, namely RRM1 and RRM2, and RRM1 specifically associates with the stem loop II of U1 snRNA (small nuclear RNA). In addition to functioning as a component of the U1 snRNP, SNRPA negatively regulates polyadenylation of SNRPA pre-mRNA, thereby negatively regulating itself. By inhibiting the addition of a polyA tail that would allow the pre-mRNA to mature, SNRPA causes the nuclear exosome degradation of the SNRPA pre-mRNA. At least 16% of cellular SNRPA also functions in an snRNP-free form (SF-A) that complexes with a group of non-snRNP proteins.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SNRPA (D-4) | sc-514390 | 200 µg/ml | $316.00 | |||
SNRPA (D-4): m-IgGκ BP-HRP Kit | sc-536283 | 200 µg Ab; 40 µg BP | $354.00 | |||
SNRPA (D-4): m-IgG2b BP-HRP Kit | sc-549531 | 200 µg Ab; 10 µg BP | $354.00 | |||
SNRPA (D-4) peptide neutralisant | sc-514390 P | 100 µg/0.5 ml | $68.00 |