Date published: 2025-9-9

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Anticorps SNRPA (D-4): sc-514390

5.0(1)
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Fiches techniques
  • L'Anticorps SNRPA (D-4) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 1-21 au niveau N-terminus de SNRPA d'origine mouse
  • recommandé pour la détection de SNRPA d'origine mouse par WB, IP, IF et ELISA
  • 2b BP-HRP">m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps SNRPA (D-4) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps SNRPA (D-4)(voir les informations relatives à la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    SNRPA (small nuclear ribonucleoprotein polypeptide A), also known as U1A (U1 snRNP protein A), is a component of the RNA spliceosome, a complex of proteins that are required for the precise excision of introns from pre-messenger RNA (pre-mRNA). Localizing to the nucleus, SNRPA contains two RRM (RNA recognition motif) domains, namely RRM1 and RRM2, and RRM1 specifically associates with the stem loop II of U1 snRNA (small nuclear RNA). In addition to functioning as a component of the U1 snRNP, SNRPA negatively regulates polyadenylation of SNRPA pre-mRNA, thereby negatively regulating itself. By inhibiting the addition of a polyA tail that would allow the pre-mRNA to mature, SNRPA causes the nuclear exosome degradation of the SNRPA pre-mRNA. At least 16% of cellular SNRPA also functions in an snRNP-free form (SF-A) that complexes with a group of non-snRNP proteins.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps SNRPA (D-4)

    sc-514390
    200 µg/ml
    $316.00

    SNRPA (D-4): m-IgGκ BP-HRP Kit

    sc-536283
    200 µg Ab; 40 µg BP
    $354.00

    SNRPA (D-4): m-IgG2b BP-HRP Kit

    sc-549531
    200 µg Ab; 10 µg BP
    $354.00

    SNRPA (D-4) peptide neutralisant

    sc-514390 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-514390 P appropriate for?

    Posée par: AbPolly
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-03-01
    • y_2025, m_9, d_1, h_4CST
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    Rated 5 de 5 de par Great Western blot data of SNRPA expression in nonGreat Western blot data of SNRPA expression in non-transfected 293T, mouse SNRPA transfected 293T NIH/3T3 and 3T3-L1 whole cell lysates. -SCBT QC
    Date de publication: 2013-09-07
    • y_2025, m_9, d_1, h_4
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    Anticorps SNRPA (D-4) est évalué 5.0 de 5 de 1.
    • y_2025, m_9, d_1, h_4
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