Semaphorins comprise a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular "semaphorin" domain of approximately 500 amino acids containing 14-16 cysteines, many blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. These semaphorin proteins regulate the growth of the axons during embryogenesis by repelling growth cones from regions of high semaphorin expression . Also designated CD108, Semaphorin 7A (SEMA7A) promotes axonal growth in the central nervous system and plays a critical role in negative regulation of T cell activation and function.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SEMA7A (D-4) | sc-376149 | 200 µg/ml | $316.00 | |||
SEMA7A (D-4): m-IgG Fc BP-HRP Kit | sc-540522 | 200 µg Ab; 10 µg BP | $354.00 | |||
SEMA7A (D-4): m-IgG1 BP-HRP Kit | sc-542179 | 200 µg Ab; 20 µg BP | $354.00 |