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SECp43, also known as tRNA (Sec) selenocysteine 1-associated protein 1 or TRNAU1AP, is a 287 amino acid member of the RRM TRSPAP protein family. Localized to the nucleus and cytoplasm, yet found more abundantly in the nucleus, SECp43 contains two RRM (RNA recognition motif) domains. The RRM domain contains two highly conserved regions: a six amino acid, hydrophobic motif (RNP-2) and an octapeptide motif (RNP-1). SECp43 is involved in the early stages of selenocysteine biosynthesis and tRNA charging. It is also involved in the later stages of the cotranslational incorporation of selenocysteine into selenoproteins. Possibly involved in the methylation of tRNA, SECp43 associates with mRNP, SELB, SBP-2 and tRNA. Two isoforms of SECp43 exist as a result of alternative splicing events.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SECp43 (F-9) | sc-390031 | 200 µg/ml | $316.00 | |||
SECp43 (F-9): m-IgG Fc BP-HRP Kit | sc-540743 | 200 µg Ab; 10 µg BP | $354.00 | |||
SECp43 (F-9): m-IgG1 BP-HRP Kit | sc-542341 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps SECp43 (F-9) X | sc-390031 X | 200 µg/0.1 ml | $316.00 |