Ribosomal Protein L14 Antibody (KQ-16): sc-100826

Ribosomal Protein L14 Antibody (KQ-16) is a mouse monoclonal IgG2a kappa light chain antibody that detects Ribosomal Protein L14 (RPL14) of human origin by immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-RPL14 antibody (KQ-16) is available as a non-conjugated format. RPL14, also known as L14, RL14, CTG-B33, or CAG-ISL-7, is a crucial component of the 60S ribosomal subunit, which plays a vital role in protein synthesis within the cytoplasm. This 213 amino acid protein belongs to the L14e family of ribosomal proteins and features a basic region-leucine zipper (bZIP)-like domain and a polymorphic polyalanine tract. The polyalanine tract is particularly significant as it helps regulate transcription, influencing gene expression and cellular function. RPL14 is encoded by multigene families that include processed pseudogenes, highlighting its evolutionary importance and regulatory complexity. RPL14′s ability to interact with various other proteins within the ribosomal assembly underscores its essential role in maintaining ribosome integrity and functionality, making RPL14 a critical target for studies related to protein synthesis and cellular metabolism.

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Ribosomal Protein L14 Antibody (KQ-16) References:

1. A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders.  |  Uechi, T., et al. 2001. Genomics. 72: 223-30. PMID: 11401437
2. Autoantibody against ribosomal protein L14 in patients with systemic lupus erythematosus.  |  Hasegawa, H., et al. 2002. Clin Exp Rheumatol. 20: 139-44. PMID: 12051391
3. Silencing the Drosophila ribosomal protein L14 gene using targeted RNA interference causes distinct somatic anomalies.  |  Enerly, E., et al. 2003. Gene. 320: 41-8. PMID: 14597387
4. Alteration of RPL14 in squamous cell carcinomas and preneoplastic lesions of the esophagus.  |  Huang, XP., et al. 2006. Gene. 366: 161-8. PMID: 16316724
5. Polymorphic CUG repeats in human mRNAs and their effects on gene expression.  |  Tian, B., et al. 2005. RNA Biol. 2: 149-56. PMID: 17114933
6. Identification of trinucleotide repeat-containing genes in human pancreatic islets.  |  Aoki, M., et al. 1996. Diabetes. 45: 157-64. PMID: 8549859
7. Distribution of the B33 CTG repeat polymorphism in a subtype of schizophrenia.  |  Bengel, D., et al. 1998. Eur Arch Psychiatry Clin Neurosci. 248: 78-81. PMID: 9684916
8. The binding sites for Xenopus laevis FIII/YY1 in the first exon of L1 and L14 ribosomal protein genes are dispensable for promoter expression.  |  De Rinaldis, E., et al. 1998. Eur J Biochem. 255: 563-9. PMID: 9738894
9. Trinucleotide repeat length variation in the human ribosomal protein L14 gene (RPL14): localization to 3p21.3 and loss of heterozygosity in lung and oral cancers.  |  Shriver, SP., et al. 1998. Mutat Res. 406: 9-23. PMID: 9920051

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Ribosomal Protein L14 Antibody (KQ-16) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Ribosomal Protein L14 Antibody (KQ-16) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Ribosomal Protein L14 Antibody (KQ-16) Specifications

Alternate Product Name: Ribosomal Protein L14

Product Clone Name: KQ-16

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 1-91

Epitope Target: Ribosomal Protein L14

Epitope Species: human

Product Reactivity/Detection: Ribosomal Protein L14

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF, IHC(P), ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Ribosomal Protein L14 Antibody (KQ-16): N/A