ACCÈS RAPIDE AUX LIENS
RBM9 (RNA binding motif protein 9), also known as RTA, fxh, FOX2, Fox-2, HNRBP2 or HRNBP2, is a 390 amino acid protein that contains one RRM (RNA recognition motif) domain. RBM9 is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. RBM9 regulates the splicing activity of the highly conserved RNA 5'-UGCAUGU-3' element, an intron splicing enhancer that is often located adjacent to tissue-specific alternative exons. RBM9 prevents binding of U2AF65 (U2 snRNP auxiliary factor large subunit) to the 3' splice site of the RNA splicing element which affects alternative splicing of tissue-specific exons. RBM9 also interacts with the ERa (estrogen receptor alpha) transcription factor and regulates ERa transcriptional activity. Eight isoforms of RBM9 exists due to alternative splicing events.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps RBM9 (E-10) | sc-271406 | 200 µg/ml | $316.00 | |||
RBM9 (E-10): m-IgG2b BP-HRP Kit | sc-548539 | 200 µg Ab; 10 µg BP | $354.00 |