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Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. PYST2 inactivates MAPK/ERK, thereby regulating the MAP kinase signaling pathway. PYST2 is overexpressed in patients with acute myelogenous leukemia (AML).
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PYST2 (C-9) | sc-377381 | 200 µg/ml | $316.00 | |||
PYST2 (C-9): m-IgG Fc BP-HRP Kit | sc-538044 | 200 µg Ab; 10 µg BP | $354.00 | |||
PYST2 (C-9): m-IgGκ BP-HRP Kit | sc-535568 | 200 µg Ab; 40 µg BP | $354.00 | |||
PYST2 (C-9): m-IgG1 BP-HRP Kit | sc-545498 | 200 µg Ab; 20 µg BP | $354.00 |