Date published: 2025-9-9

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Anticorps PTTG (C-2): sc-398471

5.0(1)
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Fiches techniques
  • L'Anticorps PTTG (C-2) est un monoclonal de souris IgG2a κ, cité dans 2 publications, fourni en 200 µg/ml
  • dirigé contre les acides aminés 1-160 de PTTG d'origine human
  • recommandé pour la détection de PTTG of mouse, rat and human origin, and PTTG2 of human origin par WB, IP, IF et ELISA
  • Voir PTTG (DCS-280): sc-56207 pour d'autres anticorps conjugués PTTG, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps PTTG (C-2) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps PTTG (C-2)(voir les informations de commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

The product of the oncogene PTTG, pituitary tumor transforming gene, is a human homolog of the anaphase-inhibitor vertebrate protein, securin. PTTG contains a basic amino-terminal domain and an acidic carboxy-terminal domain, which acts as a transactivation domain when fused to a heterologous DNA binding domain. Human PTTG is overexpressed in Jurkat and is also detected in human thymus, testis and placenta. PTTG is mainly expressed in the cytoplasm and is also partially localized to the nucleus. Vertebrate PTTG regulates the separin Esp1, which promotes chromatid separation, to overcome the cohesive forces that hold sister chromatids together. This regulatory function of PTTG suggests that defective regulation of cohesion may contribute to cancer by promoting chromosome instability. Although vertebrate PTTG shares cell-cycle functions with its yeast securin counterparts Pds1p and Cut2, none share sequence homology.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps PTTG (C-2)

sc-398471
200 µg/ml
$316.00

PTTG (C-2): m-IgG Fc BP-HRP Kit

sc-538450
200 µg Ab; 10 µg BP
$354.00

PTTG (C-2): m-IgGκ BP-HRP Kit

sc-536068
200 µg Ab; 40 µg BP
$354.00

PTTG (C-2): m-IgG2a BP-HRP Kit

sc-548307
200 µg Ab; 10 µg BP
$354.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with PTTG (C-2): sc-398471 monoclonal antibody?

Posée par: TinTin
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Répondue par: Technical Support
Date de publication: 2017-02-27
  • y_2025, m_9, d_9, h_6CST
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Rated 5 de 5 de par Very good Western blot data of PTTG expressionVery good Western blot data of PTTG expression in HCT-116 whole cell lysate. -SCBT QC
Date de publication: 2014-09-07
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Anticorps PTTG (C-2) est évalué 5.0 de 5 de 1.
  • y_2025, m_9, d_9, h_6
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