Date published: 2025-9-8

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Anticorps PTTG (3F313): sc-71947

5.0(2)
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Fiches techniques
  • L'anticorps PTTG 3F313 est un monoclonal IgG2a de souris, cité dans 2 publications, fourni en 200 µg/ml
  • élevé contre le PTTG d'origine human de pleine longueur
  • recommandé pour la détection de PTTG d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • Voir PTTG (DCS-280): sc-56207 pour d'autres anticorps conjugués PTTG, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG2a BP-HRP est le réactif secondaire recommandé pour la détection de l'anticorps PTTG (3F313) pour des applications de WB and IHC(P). Ce réactif est maintenant proposé en kit avec l'anticorps PTTG (3F313) (voir Informations pour la commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

The product of the oncogene PTTG, pituitary tumor transforming gene, is a human homolog of the anaphase-inhibitor vertebrate protein, securin. PTTG contains a basic amino-terminal domain and an acidic carboxy-terminal domain, which acts as a transactivation domain when fused to a heterologous DNA binding domain. Human PTTG is overexpressed in Jurkat and is also detected in human thymus, testis and placenta. PTTG is mainly expressed in the cytoplasm and is also partially localized to the nucleus. Vertebrate PTTG regulates the separin Esp1, which promotes chromatid separation, to overcome the cohesive forces that hold sister chromatids together. This regulatory function of PTTG suggests that defective regulation of cohesion may contribute to cancer by promoting chromosome instability. Although vertebrate PTTG shares cell-cycle functions with its yeast securin counterparts Pds1p and Cut2, none share sequence homology.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps PTTG (3F313)

sc-71947
200 µg/ml
$316.00

PTTG (3F313): m-IgG2a BP-HRP Kit

sc-546005
200 µg Ab; 10 µg BP
$354.00

What is the recommended starting dilution for Western blot for PTTG (3F313): sc-71947 monoclonal antibody?

Posée par: Cweed
Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-71947.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Répondue par: Technical Support
Date de publication: 2017-03-01
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Rated 5 de 5 de par Very goodVery good antibody. It works for WB of human, mouse, rat cell lines, and also works for IHC of human and mouse specimen slides
Date de publication: 2017-02-19
Rated 5 de 5 de par WB publishable data with human HCTWB publishable data with human HCT-116 cells - SCBT Publication Review
Date de publication: 2014-05-20
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Anticorps PTTG (3F313) est évalué 5.0 de 5 de 2.
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