Anticorps PTH (2B67): sc-71945
- L'anticorps PTH 2B67 est un monoclonal IgG1 de souris fourni en 100 µg/ml
- dirigé contre les acides aminés 53-84 de PTH d'origine human
- recommandé pour la détection de PTH peptides (aa 53-68; 53-84; 7-84; and 1-84) d'origine human, bovine et canine par WB, IP, IF et IHC(P); non cross-reactif avec synthetic Parathyroid hormone peptides (aa 1-10; 1-34; 1-38)
- Voir PTH/PTHrP-R (3D1.1): sc-12722 pour d'autres anticorps conjugués PTH, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire PTH (2B67). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
ACCÈS RAPIDE AUX LIENS
Parathyroid hormone (PTH), which is also designated parathyrin, is an 84 amino acid single chain peptide that functions to regulate calcium metabolism by raising blood levels of calcium through various mechanisms. PTH stimulates bone formation to increase bone mass and strength in rats and humans. Within the PTH molecule, the essential activity is associated with the first 34 amino acids at the amino terminus of the molecule. The gene encoding PTH maps to human chromosome 11p15.3-p15.1. Parathyroid hormone-related protein (PTH-rP) is an autocrine factor that is structurally related to PTH yet, unlike PTH, which is synthesized only by the parathyroid cells, PTH-rP is synthesized by several cell types. PTH-rP regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Isolated from the culture medium of a human lung cancer cell line, PTH-rP produces PTH-like effects that are characterized as humoral hypercalcemia of malignancy. The gene encoding PTH-rP maps to human chromosome 12p12.1-p11.2. Both PTH and PTH-rP are regulated by vitamin D and steroid hormones, and both preferentially bind to specific PTH/PTH-rP receptors, then activate adenylate cyclase or PLC β via PKC activation.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PTH (2B67) | sc-71945 | 100 µg/ml | $316.00 |