Anticorps PRMT2 (C-3): sc-514133
- L'Anticorps PRMT2 (C-3) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 221-315 dans une région interne de PRMT2 d'origine human
- recommandé pour la détection de PRMT2 d'origine human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour PRMT2 Antibody (C-3) for WB applications. Ces réactifs sont désormais proposés en lots avec PRMT2 Antibody (C-3)(voir les informations de commande ci-dessous).
PRMT2 (Protein arginine N-methyltransferase 2) is a 433 amino acid protein encoded by the human gene PRMT2. PRMT2 belongs to the protein arginine N-methyltransferase family and contains one SH3 domain. The primary function of protein methyltransferases is the post-translational methylation of arginine residues. The PRMT family of proteins contains related putative methyltransferase domains that modify chromatin and regulate cellular transcription. Some family members, PRMT1 and PRMT4, show transcriptional modulation and intracellular signaling. Through a highly conserved S-adenosylmethionine-binding domain, PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis. PRMT2 has this effect by blocking nuclear export of IkappaB-alpha through a leptomycin-sensitive pathway, which increases nuclear IkappaB-alpha and decreases NF-kappaB DNA binding. PRMT2 also renders cells susceptible to apoptosis by cytokines or cytotoxic drugs.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PRMT2 (C-3) | sc-514133 | 200 µg/ml | $316.00 | |||
PRMT2 (C-3): m-IgG Fc BP-HRP Kit | sc-540959 | 200 µg Ab; 10 µg BP | $354.00 | |||
PRMT2 (C-3): m-IgG1 BP-HRP Kit | sc-542492 | 200 µg Ab; 20 µg BP | $354.00 |