Anticorps POPX2 (G-10): sc-393806
- L'Anticorps POPX2 (G-10) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 204-269 dans une région interne de POPX2 d'origine human
- recommandé pour la détection de POPX2 d'origine human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps POPX2 (G-10) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps POPX2 (G-10)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine protein phosphatases. POPX1, also designated partner of PIX 1, PPM1E (protein phosphatase 1E) or PP2CH, and POPX2, also designated partner of PIX 2, PPM1F (protein phosphatase 1F), CaMKPase (CaM-kinase phosphatase), or FEM-2, belong to the PP2C family of serine/threonine phosphatases. Members of the PP2C family are negative regulators of cell stress response pathways. POPX2 is a ubiquitously expressed protein and POPX1 is predominantly expressed in brain and testis. POPX1 and POPX2 specifically interact with PIX (PAK interacting exchange factor) proteins and negatively regulate the activity of αPAK, a protein kinase that can lead to the breakdown of actin stress fibers and other morphological changes. POPX2 can also interact with and regulate CaMKII activity. Overexpression of POPX2 can result in caspase-dependent apoptosis.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps POPX2 (G-10) | sc-393806 | 200 µg/ml | $316.00 | |||
POPX2 (G-10): m-IgG Fc BP-HRP Kit | sc-538315 | 200 µg Ab; 10 µg BP | $354.00 | |||
POPX2 (G-10): m-IgGκ BP-HRP Kit | sc-535897 | 200 µg Ab; 40 µg BP | $354.00 | |||
POPX2 (G-10): m-IgG1 BP-HRP Kit | sc-545636 | 200 µg Ab; 20 µg BP | $354.00 |