Date published: 2025-9-11

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Anticorps POPX2 (B-11): sc-393807

5.0(1)
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Fiches techniques
  • L'Anticorps POPX2 (B-11) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 204-269 dans une région interne de POPX2 d'origine human
  • recommandé pour la détection de POPX2 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Le m-IgGκ BP-HRP est le réactif de détection secondaire préféré pour l'anticorps POPX2 (B-11) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps POPX2 (B-11)(voir les informations relatives à la commande ci-dessous). Pour d'autres conjugués m-IgGκ BP, voir notre liste complète de protéines de liaison à l'IgG de souris.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine protein phosphatases. POPX1, also designated partner of PIX 1, PPM1E (protein phosphatase 1E) or PP2CH, and POPX2, also designated partner of PIX 2, PPM1F (protein phosphatase 1F), CaMKPase (CaM-kinase phosphatase), or FEM-2, belong to the PP2C family of serine/threonine phosphatases. Members of the PP2C family are negative regulators of cell stress response pathways. POPX2 is a ubiquitously expressed protein and POPX1 is predominantly expressed in brain and testis. POPX1 and POPX2 specifically interact with PIX (PAK interacting exchange factor) proteins and negatively regulate the activity of αPAK, a protein kinase that can lead to the breakdown of actin stress fibers and other morphological changes. POPX2 can also interact with and regulate CaMKII activity. Overexpression of POPX2 can result in caspase-dependent apoptosis.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps POPX2 (B-11)

    sc-393807
    200 µg/ml
    $316.00

    POPX2 (B-11): m-IgGκ BP-HRP Kit

    sc-535898
    200 µg Ab; 40 µg BP
    $354.00

    For Western Blot, is it recommended to use denatured or non-denatured conditions with POPX2 (B-11): sc-393807 monoclonal antibody?

    Posée par: Cweed
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Répondue par: Technical Support
    Date de publication: 2017-02-27
    • y_2025, m_8, d_29, h_8CST
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    Rated 5 de 5 de par Satisfactory Western blot data of POPX2 expressionSatisfactory Western blot data of POPX2 expression in non-transfected 293T, human POPX2 transfected 293T Jurkat, MCF7 and K-562 whole cell lysates. -SCBT QC
    Date de publication: 2014-01-17
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    Anticorps POPX2 (B-11) est évalué 5.0 de 5 de 1.
    • y_2025, m_8, d_29, h_8
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