Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF13 (PHD finger protein 13), also known as PHF5 or SPOC1, is a 300 amino acid protein that contains one PHD-type zinc finger, suggesting involvement in transcriptional regulation events. The gene encoding PHF13 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PHF13 (E-4) | sc-376085 | 200 µg/ml | $316.00 | |||
PHF13 (E-4): m-IgG Fc BP-HRP Kit | sc-540508 | 200 µg Ab; 10 µg BP | $354.00 | |||
PHF13 (E-4): m-IgG1 BP-HRP Kit | sc-542168 | 200 µg Ab; 20 µg BP | $354.00 |