

PBF Antibody (NB-A25) is a mouse monoclonal IgG2a antibody that detects PBF in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). PBF, also known as PTTG1IP (pituitary tumor-transforming 1 interacting protein), is a 180 amino acid single-pass type I membrane protein that plays a crucial role in cellular signaling and transcriptional regulation. Anti-PBF antibody (NB-A25) recognizes both cytoplasmic and nuclear forms of PBF, where PBF facilitates the nuclear translocation of PTTG, a key factor in the transcriptional activation of fibroblast growth factor (FGF). This interaction is vital for various cellular processes, including cell proliferation and differentiation, making PBF an important player in developmental biology and cancer research. The gene encoding PBF is situated on human chromosome 21, a region associated with several genetic disorders, including Down Syndrome, which highlights the significance of studying this protein in the context of human health and disease. PBF monoclonal antibody (NB-A25) serves as an essential tool for researchers exploring the functional dynamics of PBF and its implications in various biological pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PBF Antibody (NB-A25) | sc-134414 | 100 µg/ml | $339.00 |