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The p21(CDKN1A)-activated kinases (PAKs) are serine/threonine protein kinases that bind to activated small GTPases, including Cdc42 and Rac, and influence transcription, cell morphology (cytoskeleton rearrangement), motility, and apoptosis. PAK family members contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK6 protein cotranslocates into the nucleus with androgen receptor, which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development, in response to androgen. PAK6 transcripts are present at high levels in brain and testis, with lower levels in multiple tissues including prostate and breast. The human PAK6 gene maps to chromosome 15q14.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps PAK6 (C-2) | sc-393102 | 200 µg/ml | $316.00 | |||
PAK6 (C-2): m-IgG Fc BP-HRP Kit | sc-538142 | 200 µg Ab; 10 µg BP | $354.00 | |||
PAK6 (C-2): m-IgGκ BP-HRP Kit | sc-535701 | 200 µg Ab; 40 µg BP | $354.00 | |||
PAK6 (C-2): m-IgG2a BP-HRP Kit | sc-548215 | 200 µg Ab; 10 µg BP | $354.00 |