ACCÈS RAPIDE AUX LIENS
Paip, for PABP-interacting protein, binds to the polyadenylate-binding protein (PABP), which in yeasts and plants has been shown to bind to the eukaryotic initiation factor component eIF4G. There are two Paip proteins called Paip1 and Paip2. Paip1 stimulates translation, and Paip2, which competes with Paip1 for binding to PABP, represses translation. Paip2 decreases the affinity of PABP for polyadenylate RNA, and disrupts the repeating structure of poly(A) ribonucleoprotein. Paip1 contains an eIF4A-binding region and a proline-rich N terminus. Overexpression of Paip1 in COS-7 cells stimulates translation, perhaps by providing a physical link between the mRNA termini. The human Paip1 gene encodes a 480 amino acid protein.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Paip1 (F-6) | sc-365188 | 200 µg/ml | $316.00 | |||
Paip1 (F-6): m-IgG Fc BP-HRP Kit | sc-537787 | 200 µg Ab; 10 µg BP | $354.00 | |||
Paip1 (F-6): m-IgGκ BP-HRP Kit | sc-535173 | 200 µg Ab; 40 µg BP | $354.00 | |||
Paip1 (F-6) peptide neutralisant | sc-365188 P | 100 µg/0.5 ml | $68.00 |