Date published: 2025-9-7

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Anticorps p53R2 (H-3): sc-137173

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Fiches techniques
  • L'anticorps p53R2 H-3 est un monoclonal IgG1 de souris fourni en 200 µg/ml
  • soulevée contre les acides aminés 52-351 correspondant à C-terminus de p53R2 d'origine human.
  • recommandé pour la détection de p53R2 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Voir R2/p53R2 (F-9): sc-376973 pour d'autres anticorps conjugués p53R2, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire p53R2 (H-3). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    The p53 gene is a highly characterized tumor suppressor that is often inactivated in various human cancers. p53 is a transcription factor that mediates cell cycle arrest and apoptosis by binding to DNA and activating the transcription of specific genes. p53 is also thought to be involved in DNA repair by the transcriptional activation of a ribonucleotide reductase gene, p53R2, after exposure to genotoxic stresses. p53R2 displays a significant similarity to ribonucleotide reductase small subunit (R2), and the expression of R2 is elevated at the onset of the S-phase of the cell cycle. However, only p53R2 expression is induced in response to ultraviolet and γ-irradiation and adriamycin treatment. p53R2 translocates to the nucleus upon DNA damage, and subsequently, supplies an immediate pool of dNTPs necessary for DNA repair.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps p53R2 (H-3)

    sc-137173
    200 µg/ml
    $316.00

    I need to use an antibody to detect the protein in samples of avian origin. Do you know if p53R2 (H-3): sc-137173 mouse monoclonal antibody will work?

    Posée par: TinTin
    Thank you for your inquiry. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity. We are available by phone, e-mail or chat.
    Répondue par: Technical Support
    Date de publication: 2017-02-27
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    Rated 5 de 5 de par Produced positive Western blot data of p53R2Produced positive Western blot data of p53R2 If expression in non-transfected and human p53R2 If transfected 293T whole cell lysates. -SCBT QC
    Date de publication: 2014-11-08
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    Anticorps p53R2 (H-3) est évalué 5.0 de 5 de 1.
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