ACCÈS RAPIDE AUX LIENS
Natural resistance associated macrophage proteins (NRAMPs) belong to a super-family of highly conserved integral membrane proteins. NRAMP 1 is an intracellular macrophage protein located at the phagosomal membrane where it functions as a divalent cation transporter for Fe2+, Zn2+ and Mn2+. NRAMP 1 is a pH-dependent antiporter that transports metal ions either into or out of the phagosome against a proton gradient. In humans, polymorphisms in the NRAMP 1 gene are linked to susceptibility to M. tuberculosis and leprosy. NRAMP 2 is another divalent cation transporter ubiquitously expressed as two splice variants, which are distinguished by the presence (isoform 1) or absence (isoform 2) of an iron response element. In the duodenum of the small intestine, dietary iron regulates NRAMP 2 expression at the brush border. Mutations in the gene for NRAMP 2 in mice and rats result in severe anemia.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NRAMP 1 (D-9) | sc-398036 | 200 µg/ml | $316.00 | |||
NRAMP 1 (D-9): m-IgG Fc BP-HRP Kit | sc-538357 | 200 µg Ab; 10 µg BP | $354.00 | |||
NRAMP 1 (D-9): m-IgGκ BP-HRP Kit | sc-535952 | 200 µg Ab; 40 µg BP | $354.00 | |||
NRAMP 1 (D-9): m-IgG2b BP-HRP Kit | sc-549945 | 200 µg Ab; 10 µg BP | $354.00 | |||
NRAMP 1 (D-9) peptide neutralisant | sc-398036 P | 100 µg/0.5 ml | $68.00 |