ACCÈS RAPIDE AUX LIENS
Notch 1 Antibody (A-8) is an IgM κ mouse monoclonal Notch 1 antibody (also designated NOTCH1 antibody) that detects the Notch 1 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. Notch 1 Antibody (A-8) is available as both the non-conjugated anti-Notch 1 antibody form, as well as multiple conjugated forms of anti-Notch 1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The LIN-12/Notch transmembrane receptors are believed to play a central role in development by regulating cell fate decisions. Four Notch homologs (Notch 1, Notch 2, Notch 3 and Notch 4) have been identified in mammals. The Notch genes are expressed in a variety of embryonic and adult tissues, suggesting that the genes are involved in multiple signaling pathways. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged1, Jagged2 and Delta. Jagged1 can activate Notch and prevent myoblast differentiation by inhibiting the expression of muscle regulatory and structural genes. Jagged2 may be involved in tissue development that is dependent upon epithelial-mesenchymal interactions. In addition to its normal expression in the adrenal gland and placenta, Delta expression has also been found in neuroendocrine tumors.
Alexa Fluor® est une marque déposée de Molecular Probes Inc., OR., USA
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Notch1 (A-8) | sc-376403 | 200 µg/ml | $316.00 | |||
Notch1 (A-8): m-IgGκ BP-HRP Kit | sc-552043 | 200 µg Ab; 40 µg BP | $354.00 | |||
Anticorps Notch1 (A-8) AC | sc-376403 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Anticorps Notch1 (A-8) Alexa Fluor® 488 | sc-376403 AF488 | 200 µg/ml | $357.00 | |||
Anticorps Notch1 (A-8) Alexa Fluor® 647 | sc-376403 AF647 | 200 µg/ml | $357.00 | |||
Anticorps Notch1 (A-8) FITC | sc-376403 FITC | 200 µg/ml | $330.00 | |||
Anticorps Notch1 (A-8) HRP | sc-376403 HRP | 200 µg/ml | $316.00 | |||
Notch1 (A-8) peptide neutralisant | sc-376403 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps Notch1 (A-8) PE | sc-376403 PE | 200 µg/ml | $343.00 |