ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
The Drosophila discs large (dlg) tumor suppressor gene was first identified in Drosophila through genetic analysis of germline mutations. Several mammalian homologs were subsequently identified and categorized into a protein family termed MAGUK (membrane-associated guanylate kinase homolog). Human homologs of dlg include hdlg-1 (rat SAP-97) and NE-dlg (neuronal and endocrine dlg). The rat synaptic protein SAP90 (also designated PSD-95) also shares homology with these proteins. MAGUKs are localized at the membrane-cytoskeleton interface and contain several distinct domains which suggest a role for these proteins in intracellular signal transduction. Interaction of hdlg-1 and NE-dlg with the tumor suppresor protein APC suggest that MAGUK proteins may also play a role in regulation of growth.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NE-dlg (D-6) | sc-376144 | 200 µg/ml | $316.00 | |||
NE-dlg (D-6): m-IgG Fc BP-HRP Kit | sc-540520 | 200 µg Ab; 10 µg BP | $354.00 | |||
NE-dlg (D-6): m-IgG1 BP-HRP Kit | sc-542178 | 200 µg Ab; 20 µg BP | $354.00 | |||
NE-dlg (D-6) peptide neutralisant | sc-376144 P | 100 µg/0.5 ml | $68.00 |