Date published: 2025-9-11

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Anticorps NANS (D-8): sc-374132

5.0(2)
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Fiches techniques
  • L'Anticorps NANS (D-8) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 1-300 situés au niveau N-terminus de NANS d'origine human
  • recommandé pour la détection de NANS d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps NANS (D-8) pour les applications WB et IHC(P). Ces réactifs sont désormais proposés en lots avec l'anticorps NANS (D-8)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Sialic acids are a family of 9-carbon 2-keto-3-deoxy sugars that are found on the ends of glycoproteins and glycolipids and play important roles in recognition events within the cell. NANS (N-acetylneuraminic acid synthase), also known as SAS, is a 359 amino acid protein that contains one AFP (antifreeze protein)-like domain and functions in the biosynthesis of sialic acids. Expressed ubiquitously, NANS enzymatically catalyzes the H2O-dependent formation of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), both of which are sialic acids. NANS uses N-acetylmannosamine 6-phosphate as a substrate for Neu5Ac synthesis and mannose 6-phosphate as a substrate for KDN synthesis. Human NANS shares 36% identity with the E. coli protein neuB, suggesting a conserved function between species.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps NANS (D-8)

    sc-374132
    200 µg/ml
    $316.00

    NANS (D-8): m-IgG Fc BP-HRP Kit

    sc-537920
    200 µg Ab; 10 µg BP
    $354.00

    NANS (D-8): m-IgGκ BP-HRP Kit

    sc-535395
    200 µg Ab; 40 µg BP
    $354.00

    NANS (D-8): m-IgG2a BP-HRP Kit

    sc-548151
    200 µg Ab; 10 µg BP
    $354.00

    Can NANS (D-8): sc-374132 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Posée par: AbPolly
    Thank you for your question. Yes, NANS (D-8): sc-374132 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Répondue par: Technical Support
    Date de publication: 2017-03-01
    • y_2025, m_8, d_28, h_5CST
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    Rated 5 de 5 de par Produced beautiful immunoperoxidase nuclearProduced beautiful immunoperoxidase nuclear and cytoplasmic staining in formalin fixed, paraffin-embedded human rectum tissue. -SCBT QC
    Date de publication: 2015-05-01
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    Anticorps NANS (D-8) est évalué 5.0 de 5 de 2.
    • y_2025, m_8, d_28, h_5
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