Date published: 2025-9-10

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Anticorps NALP2 (E-5): sc-365935

5.0(2)
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Fiches techniques
  • L'Anticorps NALP2 (E-5) est un monoclonal de souris IgG1 κ, cité dans 2 publications, fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 159-193 près de N-terminus de NALP2 d'origine human
  • recommandé pour la détection de all isoforms of NALP2 d'origine human par WB, IP, IF et ELISA
  • m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps NALP2 (E-5) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps NALP2 (E-5)(voir les informations de commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

NALP2 (PAN1, PYPAF2) is a 1,062 amino acid protein that catalyzes the suppression of TNF- and CD40-induced NFKB1 activity at the level of the IKK complex by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, NALP2 activates CASP1, which leads to the secretion of mature proinflammatory cytokine IL1B. As a putative member of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1, NALP2 may be involved in the activation of proinflammatory caspases. NALP2 shows predominant expression in lung, placenta and thymus tissues, and demonstrates lower levels of expression in ovary, intestine and brain tissues. NALP2 contains 1 DAPIN domain, 9 LRR (leucine-rich repeats) and 1 NACHT domain. The DAPIN domain is crucial for the suppression of NFKB1 activation and for inducing IL1B secretion in collaboration with caspase-1.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps NALP2 (E-5)

sc-365935
200 µg/ml
$316.00

NALP2 (E-5): m-IgG Fc BP-HRP Kit

sc-537853
200 µg Ab; 10 µg BP
$354.00

NALP2 (E-5): m-IgGκ BP-HRP Kit

sc-535280
200 µg Ab; 40 µg BP
$354.00

NALP2 (E-5): m-IgG1 BP-HRP Kit

sc-545404
200 µg Ab; 20 µg BP
$354.00

NALP2 (E-5) peptide neutralisant

sc-365935 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-365935 P appropriate for?

Posée par: jerojero
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Répondue par: Technical Support
Date de publication: 2017-03-01
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Rated 5 de 5 de par Produced great immunofluorescence cytoplasmicProduced great immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date de publication: 2015-05-15
Rated 5 de 5 de par Produced positive Western Blot data of NALP2Produced positive Western Blot data of NALP2 expression in K-562 whole cell lysate. -SCBT QC
Date de publication: 2013-04-10
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Anticorps NALP2 (E-5) est évalué 5.0 de 5 de 2.
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