The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 (also designated macrophage metalloelastase) is produced in alveolar macrophages and degrades elastin. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders.
Alexa Fluor® est une marque déposée de Molecular Probes Inc., OR., USA
LI-COR® et Odyssey® sont marques déposées de LI-COR Biosciences
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps MMP-12 (H-9) | sc-390284 | 200 µg/ml | $316.00 | |||
MMP-12 (H-9): m-IgG Fc BP-HRP Kit | sc-538076 | 200 µg Ab; 10 µg BP | $354.00 | |||
MMP-12 (H-9): m-IgGκ BP-HRP Kit | sc-535610 | 200 µg Ab; 40 µg BP | $354.00 | |||
MMP-12 (H-9): m-IgG2a BP-HRP Kit | sc-548200 | 200 µg Ab; 10 µg BP | $354.00 | |||
MMP-12 (H-9) peptide neutralisant | sc-390284 P | 100 µg/0.5 ml | $68.00 |