Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
ACCÈS RAPIDE AUX LIENS
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Mitogen-inducible gene 6 protein (Mig-6), also designated Gene 33 or RALT, belongs to the Mig-6 family. The gene encoding for Mig-6 maps to chromosome 1p36.12-p36.33. Mig-6 is a cytoplasmic protein acting as a feedback inhibitor of ErbB-2 mitogenic function and can suppress ErbB-2 oncogenic activity. The expression of Mig-6 is upregulated with cell growth. Mig-6 binds to the epidermal growth factor receptor (EGFR) upon EGF stimulation and is considered a negative feedback regulator of EGFR and a potential tumor suppressor. Mig-6 induces transcriptional activation of NFκB by binding to its inhibitor IκB-α. It enables the cell to respond persistently to chronic stress. Mig-6 mRNA levels increase in response to stress such as diabetic nephropathy, vasoactive peptides or mechanical strain. Mig-6 is expressed in liver, placenta and lung.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.