Anti-L'anticorps megsin H-10 est un monoclonal IgG1 (chaîne légère kappa) L'Anticorps megsin fourni en 200 µg/ml
dirigé contre les acides aminés 32-165 situés près du N-terminus de megsin de human
Anti-L'Anticorps megsin (H-10) est recommandé pour la détection de megsin d'origine mouse, rat et human par WB, IP, IF et ELISA
Anti-L'Anticorps megsin (H-10) est disponible conjugué à l'agarose pour IP; à l'HRP pour WB, IHC(P) et ELISA; et soit à la phycoerythrin ou FITC pour IF, IHC(P) et FCM
aussi disponible conjugué à l'Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 ou Alexa Fluor® 647 pour WB (RGB), IF, IHC(P) et FCM
aussi disponible conjugué à l'Alexa Fluor® 680 ou Alexa Fluor® 790 pour WB (NIR), IF et FCM
Contactez notre Service Technique (ou votre Distributeur local) pour plus d'informations pour recevoir un échantillon GRATUIT de 10 µg de megsin (H-10): sc-515694.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for megsin Antibody (H-10) for WB applications. This reagent is now offered in a bundle with megsin Antibody (H-10) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
megsin Antibody (H-10) is a high quality monoclonal megsin antibody (also designated megsin antibody) suitable for the detection of the megsin protein of mouse, rat and human origin. megsin Antibody (H-10) is available as both the non-conjugated anti-megsin antibody form, as well as multiple conjugated forms of anti-megsin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Megsin, also designated SerpinB7 and TP55, is a 380 amino acid cytoplasmic protein that is predominantly expressed in mesangial cells, which play an important role in maintaining glomerular structure and function. As a member of the serpin family, megsin is a serine protesase inhibitor which potentially inactivate MMP-2, MMP-9 and plasmin, proteins that are notably responsible for degradation of extracellular matrix. Overexpression of megsin results in an increase in number of mesangial cells and therefore a progressive mesangial matrix expansion, which is accompanied by immune complex deposition. This finding suggests that megsin significantly influences the role of mesangial cells in renal structure and is likely implicated in a variety of nephropathies.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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