Anticorps Med7 (E-7): sc-101188
- L'Anticorps Med7 (E-7) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 100 µg/ml
- dirigé contre la Med7 recombinante d'origine human
- recommandé pour la détection de Med7 d'origine mouse, rat et human par WB, IP et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire Med7 (E-7). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase. These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors. Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation. Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Med7 (E-7) | sc-101188 | 100 µg/ml | $333.00 |