Anticorps Mcm4 (D-7): sc-166037
- L'Anticorps Mcm4 (D-7) est un monoclonal de souris IgG2a κ, cité dans 2 publications, fourni en 200 µg/ml
- soulevée contre les acides aminés 1-300 correspondant à N-terminus de Mcm4 d'origine Saccharomyces cerevisiae.
- recommandé pour la détection de Mcm4 d'origine y par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps Mcm4 (D-7) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps Mcm4 (D-7)(voir les informations de commande ci-dessous).
The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1 to S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the postreplicative state of the cell. MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro. Cleavage of MCM3, which can be prevented by caspase inhibitors, results in the inactivation of the MCM complex (composed of at least MCM proteins 2-6) during apoptosis. A complex composed of MCM4, MCM6 and MCM7 has been shown to be involved in DNA helicase activity, and MCM5 is involved in IFN-γ-induced Stat1α transcription activation.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Mcm4 (D-7) | sc-166037 | 200 µg/ml | $316.00 | |||
Mcm4 (D-7): m-IgG Fc BP-HRP Kit | sc-537431 | 200 µg Ab; 10 µg BP | $354.00 | |||
Mcm4 (D-7): m-IgGκ BP-HRP Kit | sc-534695 | 200 µg Ab; 40 µg BP | $354.00 | |||
Mcm4 (D-7): m-IgG2a BP-HRP Kit | sc-548014 | 200 µg Ab; 10 µg BP | $354.00 |