Anticorps LMP2 (A-1): sc-271354
- L'Anticorps LMP2 (A-1) est un monoclonal de souris IgG2a κ, cité dans 3 publications, fourni en 200 µg/ml
- soulevée à l'encontre des acides aminés 20-219 représentant l'intégralité de la protéine mature LMP2 mature d'origine human.
- recommandé pour la détection de precursor and mature forms of LMP2 d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps LMP2 (A-1) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps LMP2 (A-1)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
The eukaryotic multicatalytic proteinase complex, otherwise known as the proteasome, is present in both the nucleus and cytoplasm of cells and contains at least 15 nonidentical subunits, which form a highly ordered ring-shaped structure. The proteasome is involved in an ATP/Ubiquitin-dependent proteolytic pathway and expresses at least five distinct proteolytic activities, including the cleavage of peptides after branched chain amino acids or bulky hydrophobic amino acids. Two components of the proteasome are the low molecular mass proteins LMP2 and LMP7, which are thought to connect the proteasome to the MHC class-I antigen-processing pathway. Upon stimulation with IFN-γ, LMP2 and LMP7 displace housekeeping subunits in the proteasome and activate cytotoxic T cells (CTLs). LMP2 and LMP7 are produced as precursor proteins, which are processed to subunits that have the ability to complex with the proteasome. LMP2 is expressed as two alternatively spliced forms, LMP2.l and LMP2.s, in lymphoblastoid cell lines and in fibroblasts after IFN-γ stimulation. LMP7 is also expressed as two forms, LMP7-E1 and E2, in several tissues.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps LMP2 (A-1) | sc-271354 | 200 µg/ml | $316.00 | |||
LMP2 (A-1): m-IgG Fc BP-HRP Kit | sc-537621 | 200 µg Ab; 10 µg BP | $354.00 | |||
LMP2 (A-1): m-IgGκ BP-HRP Kit | sc-534938 | 200 µg Ab; 40 µg BP | $354.00 | |||
LMP2 (A-1): m-IgG2a BP-HRP Kit | sc-548069 | 200 µg Ab; 10 µg BP | $354.00 |