ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
Lambda 5 (also called Immunoglobulin lambda-like polypeptide 1 or CD179b antigen) and VpreB comprise the surrogate light chain of the pre-B cell receptor complex. SL chain is also part of a quality control mechanism that tests a m-chain for its ability to pair with conventional L chains. It can form Ig-like complexes with the heavy (H) chain, the DHJHC m-protein or the p55 chain. Production of the surrogate light chain begins at the stage of pro-B cells, continues during the pre-B-cell stage and halts at the immature B cell stage. Once pre-BCR is expressed, SL chain expression is turned off. As pre-B II cells proliferate, SL is diluted out, thus limiting pre-BCR formation. Lambda 5 is critical for B cell development in mammals. Expression of Lambda 5 is highest in liver, pre- B-lymphocytes and bone marrow, the major source of B cell precursors.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Lambda 5 (G-12) | sc-398037 | 200 µg/ml | $316.00 | |||
Lambda 5 (G-12) peptide neutralisant | sc-398037 P | 100 µg/0.5 ml | $68.00 |