Date published: 2025-9-6

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Anticorps JAK3 (A1-14-16): sc-56921

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Fiches techniques
  • L'anticorps JAK3 A1-14-16 est un monoclonal IgG2a de souris, cité dans 2 publications, fourni en 200 µg/ml
  • dirigé contre les acides aminés 1076-1100 de JAK3 d'origine mouse
  • recommandé pour la détection de JAK3 d'origine mouse, rat et human par WB, IP, IF et IHC(P); non cross-reactif avec JAK 1, JAK 2 or Tyk 2
  • Voir JAK3 (B-12): sc-6932 pour d'autres anticorps conjugués JAK3, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire JAK3 (A1-14-16). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

JAK3 (Janus kinase 3) belongs to the family of non-receptor Janus tyrosine kinases, which regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Immunological stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK3. JAK3 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription. The canonical JAK/Stat pathway is integral to maintaining a normal immune system, stimulating proliferation, differentiation, survival and host resistance to pathogens. Altering JAK/Stat signaling to reduce cytokine induced pro-inflammatory responses represents an attractive target for anti-inflammatory therapies.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps JAK3 (A1-14-16)

sc-56921
200 µg/ml
$316.00

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-56921: JAK3 (A1-14-16) mouse monoclonal antibody will work?

Posée par: DefinitelyNotMatt
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Répondue par: Technical Support
Date de publication: 2017-03-06
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Rated 5 de 5 de par Popular antibodyThis monoclonal antibody is a popular clone for JAK3 detection.
Date de publication: 2017-02-08
Rated 4 de 5 de par It has been reported in literature that thisIt has been reported in literature that this antibody is suitable for use in WB using human SU-DHL-1 and Karpas 299 and SUP-M2 cells. -SCBT Publication Review
Date de publication: 2014-03-08
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Anticorps JAK3 (A1-14-16) est évalué 4.5 de 5 de 2.
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