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Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with delta heavy chains and either kappa or lambda light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps IgD (AMS 9.1) | sc-53853 | 200 µg/ml | $316.00 | |||
IgD (AMS 9.1): m-IgG Fc BP-HRP Kit | sc-537005 | 200 µg Ab; 10 µg BP | $354.00 | |||
IgD (AMS 9.1): m-IgGκ BP-HRP Kit | sc-534185 | 200 µg Ab; 40 µg BP | $354.00 | |||
Anticorps IgD (AMS 9.1) FITC | sc-53853 FITC | 200 µg/ml | $330.00 | |||
Anticorps IgD (AMS 9.1) L | sc-53853 L | 200 µg/0.1 ml | $316.00 | |||
Anticorps IgD (AMS 9.1) PE | sc-53853 PE | 200 µg/ml | $343.00 |